Scientific Program - The First World Congress on Controversies in Gastroenterology & Liver Diseases (CGoLD)

The 1st World Congress on
Controversies in Gastroenterology & Liver Diseases (C-GOLD)

Scientific Program

Session 1

Colorectal Cancer

Capsule	Colorectal cancer screening policies vary significantly
Debate	What is the Best Screening Method for Colorectal Cancer? Colonoscopy Fecal occult blood test Newer technologies will yield better results
Capsule	No agreement exists on the optimal treatment of metastatic colon cancer
Debate	Metastatic Colorectal Cancer should be Treated Upfront with Chemotherapy and Biologicals Pro / Con
Debate	Colorectal Cancer Liver Metastases: Aggressive Oncologists and Surgeons: Are they right? Yes / No

Session 2

Barrett's Esophagus

Capsule

Screening for Barrett's esophagus, ablation of nondysplastic metaplasia, and treatment of superficial carcinoma remain highly controversial

Debate

Detect and Treat for all Cases of Barrett's Esophagus/Metaplasia
and/or Low-Grade Dysplasia

Yes / No

Debate

Endoluminal Therapy is the Standard of Care for Superficial Adenocarcinoma

Yes / No

Session 3

Perioperative Therapy in Esophagogastric and Rectal Cancers

Capsule

The impact and timing of perioperative therapy for esophagogastric and rectal cancer remains controversial

Debate

Perioperative Therapy is the Standard of Care

Pro / Con

Session 4

Hepatocarcinoma

Capsule

Policy for early detection and management of hepatocarcinoma remains debatable

Debate

Ultrasound and Alpha-Fetoprotein are Sufficient for Early Detection

Pro/ Con

Debate

Molecular-Targeted Therapies are the Standard of Care

Pro/ Con

Session 5

Chemoprevention in Gastrointestinal (GI) and Colon Cancers

Capsule	Does chemoprevention have a role in GI and colon cancer?
Debate	Chemoprevention in GI Cancer Myth / Fact
Debate	Chemoprevention of Colon Cancer in IBD Myth / Fact

Session 6

Gastrointestinal Bleeding

Capsule	Controversies remain regarding optimal timing and management tools for upper GI bleeding
Debate	Peptic Ulcer Bleeding: A Consensual Algorithm for Treatment? High doses proton pomp inhibitor and endoscopy for everyone A tailored approach with special focus on patients with platelets anti-agregant
Debate	Variceal Bleeding: Immediate Drugs or Endoscopy? Drug therapy is the main-stay of management Endoscopy and selective TIPS play the major role for treatment and prevention
Debate	Obscure GI bleeding: Capsule for Everyone, or Push and Pull Endoscopy Upfront? Capsule endoscopy remains the ideal diagnostic tools in every case Push and pull enteroscopy upfront saves time and money

Session 7

Pancreatitis

Capsule	The role and time of resection, chemotherapy and antihormonal therapy remain unclear
Debate	Painful Chronic Pancreatitis: A Tailored Multidisciplinary Approach or a Surgical Disease? Surgery is the main-stay of pain treatment in every case A tailored multidisciplinary approach with selected surgical indication is preferable
Debate	Management of Pancreatic Neuroendocrine Tumors Pro: Resect them all when resectable Con: A tailored approach

Session 8

Severe Acute Pancreatitis

Capsule	Medical management of severe acute pancreatitis is controversial
Debate	Acute Pancreatitis: Early Enteral Feeding for Everyone Pro / Con
Debate	Antibiotic Prophylaxis for Pancreatic Necrosis Antibiotic prevention of necrosis infection saves lives Antibiotic should be given only when infection is confirmed

Session 9

Inflammatory Bowel Diseases (IBDs)

Capsule	Predicting the natural history and response to treatment of Crohn's disease is potentially of major clinical importance
Debate	Can We Predict the Natural History and the Responses to Therapy of Crohn's Disease? Yes / No
Debate	Biomarkers for Diagnosis, Prediction Course, Prediction / Monitoring Treatment Pro / Con

Session 10

Treatment of IBDs

Capsule	Biologics are the cornerstone therapy in IBDs. The place of other drugs is changing
Debate	Is Early Treatment of CD with Biologics More Effective in the Short or Long Term? Short term / Long term
Debate	Is there Still a Place for 5 ASA in IBD? Yes / No

Session 11

Capsule Endoscopy


Debate	The Role of (Small Bowel) Capsule Endoscopy in IBD: Are Jejunal Lesions Clinically Relevant? Yes / No

Session 12

Endoscopy and Diagnosis

Capsule	New technologies allow tissue characterization and histological diagnosis
Debate	Narrow Band Imaging: Electronic Colorations in Addition to High-Definition Endoscopy: Do They Improve our Routine Diagnosis? Yes: As shown by many studies No: Literature is controversial and its routine use is questionable
Debate	Confocal Microscopy, Endocytoscopy: Will They Revolutionize Endoscopic / Pathological Diagnosis? A fascinating tool for research with potential major clinical application Interesting techniques, very far from clinical use

Session 13

Endoscopic Therapy for the GI Tract

Capsule	Therapeutic endoscopy still offers new possibilities: Major questions will be who, how and where
Debate	Endoscopic Submucosal Dissection: Are the Japanese Standards Applicable in Europe? Yes: We must organize ourselves in the interest of the patients No: Resources and cost will continue to prevent it
Debate	Metabolic Endoscopy for the Treatment of Obesity and Diabetes: Will the Endoluminal Approach Become a Credible Alternative to Surgery? Yes Maybe, but the role of gastroenterologists will be limited No, laparoscopic approach will remain far ahead

Session 14

Gastroesophageal Reflux Disease (GERD)

Capsule	Refractory and atypical GERD symptoms remain a challenging clinical problem
Lecture	Refractory GERD: Is there an accepted definition?
Debate	Atypical GERD Symptoms: How can the Link be Proven? Patients should be investigated off therapy Patients should be investigated on therapy
Debate	Management of the Nonresponder: Is there Room for Surgery and/or Endoluminal Therapy in Refractory GERD Yes / No

Session 15

Dyspepsia and Irritable Bowel Diseases

Capsule	The role of Helicobacter Pylori is established, but management remains controversial
Debate	Dyspepsia: Test and Treat? Treat and Test? Or Perform Endoscopy First? Treat and test or test and treat are the best options Perform endoscopy first is the preferred choice

Capsule	Knowledge of IBS is changing and it may have major consequences in management
Debate	IBS: Sensory Motor Disorder or Low-Grade IBD? The evidence for sensory motor disorder The arguments for Low Grade IBD The consequences for drug development

Session 16

Nutrition

Capsule	Nutritionists are playing an increasing role in gastroenterology and GI oncology, but their role remains debatable in several indications
Debate	Bariatric Surgery and the Bariatric Patient: Should the Nutritionist be the Major Decision Maker of Treatment Options? Yes No: The surgeon is in the best position to concentrate the opinions and propose the treatment True multidisciplinarity improves the results
Debate	Nutritional support in IBD: Is it Useful, and When? When the evidence for extending clinical use presents Should only be used in highly selected cases
Debate	Cancer-Related Malnutrition: To be Prevented, or to be Treated? Should be prevented and this has proven clinical efficacy Should be treated only

Session 17

Hepatitis B Virus (HBV)

Capsule	Treatment algorithm remains controversial
Lecture	Current treatment overview
Debate	Guidelines of the EASL vs. AASLD Issue: Indication for Initiating Nucleosides in Mild Disease: Is HbeAg Still Relevant? Yes / No
Debate	Add-on vs. Switch for Resistances to Nucleosides Add on / Switch
Lecture	Nonresponder HBV: For what duration should the domino game be played?

Session 18

Hepatitis C Virus (HCV)

Capsule	Indications for treatment and treatment options remain controversial
Debate	HCV-Positive Patients with Normal Liver Enzymes: To Treat or Not to Treat? The evidence for treatment The case not to be treated
Debate	Non-Responder Genotype 1b with Advanced Fibrosis Wait for a new treatment Continue
Lecture	Current and future treatments: The impact of decision-making today

Session 19

Liver Cirrhosis

Capsule	Diagnostic strategy is changing, and clinical course is a topic for debate
Debate	Assessment of Fibrosis: Invasive vs. Non-invasive Methods Histology will remain the gold-standard Non-invasive methods will replace it and provide more information
Debate	Controversies in Pathology: Is Cirrhosis of the Liver a Reversible Disease? Yes / No

Session 20

Miscellaneous

Capsule	Prompt adequate management of severe liver failure is mandatory, but may vary with etiology
Lecture & Debate	Drug-induced liver injury vs. necessity for treatment How do you cope?
Lecture & Debate	NAFLD/NASH: Is there a Consensual Algorithm for Diagnosis and Treatment?
Debate	Acute vs. Acute-In Chronic Liver Failure: Prompt Management is More Important than Differential Diagnosis Prompt management is the main-stay Differential diagnosis and its clinical impact