Main Topics
| Introduction to Genetics |
| Basic principles for the non-geneticist |
| Next generation sequencing: strategies for genetic testing |
| Technical aspects of reproductive genetics (Methods of PGS, PGD, Prenatal) |
| Carrier screening of recessive disease: Universal screening |
| PGD and PGS: State-of-the-Art |
| Development and current best practice for translocations |
| Single gene diagnosis and aneuploidy detection using karyomapping |
| Clinically evaluating NGS and its extra information |
| PGS for advanced maternal age |
| The clinical value of Preimplantation Genetic Screening (PGS) |
| Management of PGS treatment embryo: timing, technology, success and cost effectiveness |
| Aneuploidy in embryos: variability between centers, between patients and between cycles of the same patients |
| Debate: Is it now unethical not to screen out an aneuploidy embryo in IVF? |
| Prediction of Gamete quality and viability |
| Cumulus cell genomics and its predictive value |
| Blastocoel analysis for PGS and the potential clinical value of mitochondrial screening assays |
| Ultra-sensitive mass spectrometry to look at the proteomic content of the blastocoel fluid with a view to embryo viability assessment |
| Update on polar body testing for detection of female meiotic errors |
| Non-Invasive Prenatal Testing (NIPT): Current state of the ART |
| Introduction of NIPT in clinical practice |
| Debate: How should NIPT be used: - As primary screening to all patients - As contingent screening in very high and intermediate risk patients |
| Non-Invasive Prenatal Testing (NIPT): Future Perspectives |
| Debate: NIPT for microdeletion syndromes Pros Cons |
| NIPT for Single-Gene Disorders |
| Future development in NIPT |
| Chromosomal microarrays (CMA) in Prenatal Diagnosis |
| Chromosomal microarrays - how does it work? |
| Can CMA replace standard karyotyping? |
| Counseling for Variants of Unclear Clinical Significance |
| Debate: Would it be ethical not to propose women to undergo invasive testing with CMA? For Against |
| Genetics in infertility |
| Characterization of the molecular etiology of severe cases of infertility - a must to bring personalized medicine to the field of reproduction |
| Carrier screening of genes relevant in infertility, including mutations associated with miscarriage |
| Gene therapy in reproductive medicine |
| Social and legal aspects |
