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Controversies in Obstetrics, Gynecology & Infertility (COGI)
November 27 - 30, 2008, Paris, France
 
  Infertility & ART (I)
 
Thursday, November 27, 2008
18:30-20:00          Welcome Reception
                           at the Le Meridien Montparnasse Hotel
Friday, November 28, 2008
08:30-10:00
Plenary Session
Keynote Lecture: Advances in Ob/Gyn and Infertility
LEADERS' VIEW ON THE FUTURE
Capsule:
Technology-based diagnosis allows better and minimally-invasive treatments; What the future holds for our main sub-disciplines?
Chairpersons: 
 
 
Z. Ben Rafael, Israel
G.C. Di Renzo, Italy
R. Frydman, France
Z. Shoham, Israel
 
08:30-09:00
Feto-Maternal medicine
The future of prenatal diagnosis. Invasive or non Invasive?
K. Nicolaides, UK
 
09:00-09:30
Gynecology
The future of endoscopic surgery and the future surgeon. Robots with brain!
C. Nezhat, USA
 
09:30-10:00
Infertility 
ART: Reflecting on its future
J. Cohen, USA
 
10:00-10:30
 
Coffee break
 
10:30-12:30

MILD STIMULATION FOR IVF

Organized and endorsed by the International Society for Mild Approaches in Assisted Reproduction (ISMAAR)
Capsule:
Results of monofollicular stimulation per initiated cycle are too low and dropout is too high to make it a viable option for routine IVF!
Chairpersons:
 
 
R. Frydman, France
G. Nargund, UK
10:30-11:15
Debate: Mild/Modified Natural Cycle IVF Should be the Way Forward With the Introduction of Single Embryo Transfer (SET)
Proposition: Results are good without the risk: That is the future of IVF!
G. Nargund, UK
Opposition: Results are too low and dropout is too high to make it a viable option!
R. Fanchin, France

Discussion
 
11:15-12:00
Debate: To Achieve the Maximum Benefit. In Vitro Maturation (IVM) Cycle Should be Combined with Natural Cycle IVF in Ovulatory Women
No:   S. Lindenberg, Sweden
Yes: R.C. Chian, Canada

Discussion
 
12:00-12:30
 
12:30-13:30
 
Lunch break
 
13:30-15:30
ROUND TABLE DISCUSSION: CLINICAL ASPECTS OF ART
Capsule:
Expert opinion and audience interaction on controversial clinical aspects of ART
 
Chairpersons:
Z. Ben Rafael, Israel
J. Belaisch-Allart, France
 
Panellists:
 
 
 
S. Daya, Canada
P.G. Crosignani, Italy
K. Diedrich, Germany
N. Gleicher, USA
R. Frydman, France
 
Discussion:
Questions to the panelists:
Should we omit all treatments and move directly to IVF?
Natural cycles for IVF, or mild stimulation?
Starting dose of gonadotropins: Low or regular?
Is there evidence to support the routine use of oral contraceptives in ART cycles?
Why did the antagonist not replace the agonist?
Do we need the addition of luteinizing hormone (LH) for ovarian stimulation?
Intra Cytoplasmic Sperm Injection (ICSI) for all patients?
Assisted zona hatching: Should we keep doing it?
How can embryo transfer be improved?
Should we routinely support the luteal phase with progesterone, aspirin or estradiol?
 
 
15:30-16:00
 
Coffee break
 
16:00-18:00
ASSESSMENT OF OVARIAN RESERVE 
Capsule:cussion:
Decreased ovarian reserve remains a common and frustrating problem despite years of experience. Can we evaluate and provide better treatment? 
Chairpersons:
 
P.G. Crosignani, Italy
J. Blankstein, USA
 
16:00-16:15
 
16:15-16:55
Debate: Anti-Mullerian Hormone (AMH) or Antral Follicle Count: Which should be the Gold Standard for Evaluation of the Ovarian Follicular Status in 2008?
AMH is superior!
R. Fanchin, France
Follicular count is easy, inexpensive and reliable!
S. Lenz, Denmark
Discussion
 
16:55-17:15
What should be the first-line treatment for unexplained infertility in women over 40 years of age: Superovulation and IUI, or IVF?
N. Laufer, Israel
 
17:15-18:00
Proposition: No treatment options for Decreased Ovarian Reserve and Low Responders are effective. It is only cycle-to-cycle variation that is of importance!
P. Patrizio, USA
Opposition: Better protocols will result in better pregnancy rates!
M. Surrey, USA
Discussion
 
 
Saturday, November 29, 2008
This section is being organized and endorsed by Serono Symposia International Foundation (SSIF)
Conference Celebrate 30 years of IVF: New Technology in Reproductive Medicine
 
 08:15-08:20
 
 
Welcome from SSIF
J-D. Baki, SSIF Board of Directors
R. Fischer, Germany
 
08:20-08:30
Introductions to the Conference
Z. Shoham, Israel
 
 
08:30-10:00
STEM CELLS FOR REPRODUCTIVE AND REGENERATIVE MEDICINE
Capsule:             
Organized and endorsed by Serono Symposia International Foundation
Stem-cell-based medicine: What are the expectations? What is feasible?
 
 
Chairpersons:on
 
 
:
Y. Verlinsky, USA  
G.P. Palermo, USA
N. Frydman, France
 
08:30-09:00
 
 
Where are we now in the understanding of endometrial stem cells?
C. Simón, Spain
09:00-09:30
 
 
Can stem cells serve as a source of gametes?
A. Marques, Spain
09:30-10:00
Reprogramming as a new approach to obtain patient-specific stem cells
R. Ensenat-Waser, Spain
 
10:00-10:30
 
Coffee break
 
10:30-12:30   
IN VITRO MATURATION (IVM)
Organized and endorsed by Serono Symposia International Foundation
Capsule:
IVM is becoming more effective: Benefits, risk and pitfalls of the procedure
 
Chairpersons:
R. Frydman, France
H.I. Nielsen, Denmark
A. Weissman, Israel
 
10:30-11:10
Debate: Can IVM Now be Offered as a Treatment?
IVM is ready as a treatment for PCOS patients
M. Leong, Hong Kong
IVM is not ready as a treatment
K.R. Held, Germany
Discussion
 
 
11:10-11:50
Debate: What is the Optimum Preparation for IVM?
FSH priming for IVM
A.L. Mikkelsen, Denmark
hCG priming for IVM
R.C. Chian, Canada
Discussion 
 
 
11:50-12:30
Debate: IVM and Fertility Preservation
The role of IVM in the preservation of fertility
S.L. Tan, Canada
Efficiency of IVM treatment
R. Fadini, Italy
Discussion
 
12:30-13:30
 
Lunch break
 
13:30-15:30 CRYOPRESERVATION OF GAMETES AND OVARIAN TISSUE
Organized and endorsed by Serono Symposia International Foundation
Capsule:
The optimum method for cryopreserving oocytes and ovarian tissue is yet to be decided
 
Chairpersons:
Z. Rosenwaks, USA
P. Patrizio, USA
C. Poirot, France
 
13:30-14:00
 
 
What do we know and what is our future course?
R. Gosden, USA
14:00-15:30
Debate: What are the Best Methods for the Cryopreservation of Human Oocytes?
Human oocyte cryopreservation: The slow freezing technique
A. Borini, Italy
Autotransplantation of frozen human ovarian tissue and follicles
J. Donnez, Belgium
Whole ovary cryopreservation and transplantation in sheep
B. Salle, France
Discussion
 
15:30-16:00
Coffee break
 
16:00-17:30
NEW CRYOTECHNOLOGIES FOR GAMETES, OVARIAN TISSUE AND STEM CELLS
Organized and endorsed by Serono Symposia International Foundation
Capsule:
New cryopreservation technologies can enhance clinical results 
 
Chairpersons:
 
 
 
R. Gosden, USA
A. Arav, Israel
J. Dor, Israel
16:00-16:30
  
Human oocyte cryopreservation: Vitrification techniques
J. Liebermann, USA
16:30-16:50 Freezing whole human ovaries
P. Patrizio, USA
16:50-17:10
Freezing/drying of spermatozoa
J. Biggers, USA
17:10-17:50
Freeze/drying of stem cells
A. Arav, Israel
 
17:30-18:05
 
SPECIAL LECTURE IN HONOUR OF PROF. ROBERT EDWARDS, UK
 
 Chairpersons:
V. Gomel, Canada
R. Frydman, France
 
Reproductive medicine in the era of the personal genome
A. Handyside, UK
 
 
 
Sunday, November 30, 2008
 
08:30-10:00 CONTROLLED OVARIAN STIMULATION
Sponsored in part by an unrestricted grant from Ferring France
Capsule:
Is there a relationship between follicle growth and cocyte-cumulus complex? What is the clinical implication?
Chairperson:
 
 
R. Gosden, USA
C. Simon, Spain
J.F. Velez De La Calle, France
 
08:30-09:00
 
 
09:00-09:30
 
 
Oocyte morphology and outcome: Lessons from IVF
N. Frydman, France
09:30-10:00
 
 
 
10:00-10:30
 
Coffee break
 
10:30-12:30 POLYCYSTIC OVARIAN SYNDROME (PCOS)
Supported by International society of IVF (ISIVF)

Capsule:

PCOS is a risk factor for insulin resistance: Are all PCOS patients at risk?
 
Chairpersons:
 
 
P.Patrizio, USA
J.N. Hugues, France
A. Requena, Spain
 
10:30-11:00
 
 
 
11:00-11:45
Debate: Should Metformin be Routinely Used in Infertile Patients with PCOS?
Yes: S. Daya, Canada
Cons: Systemic review does not show consistent effect!
P. Bouchard, France
Discussion
 
 
11:45-12:30
Debate: Treating Anovulatory PCOS Patient; What should be the First Choice?
Ovulation induction?
S. Daya, Canada
Ovarian Drilling?
H. Fernandez, France
IVM
S.L. Tan, Canada
Discussion 
 
 
 
 
 
 
 

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