| 08:00 – 09:00 |
Registration |
| 09:00
– 09:45 |
Opening ceremony
Richard Insel (JDRF)
Michael White (JDRF)
Lior Reitblatt (JDRF Israel)
Shulamit Nuss (JDRF Israel)
Itamar Raz (D CURE Israel)
Jesse Roth (D Cure USA)
Avi Israeli (Ministry of Health)
|
| 09:45 – 10:30 |
Keynote lecture
Chair: Nurit Kaiser (Jerusalem)
Allen Spiegel (New York)
Strategies and vision for research on islet biology and diabetes
|
| 10:30 – 11:00 |
Coffee break |
| 11:00 – 13:00 |
Session #1
Autoimmunity and prevention of type 1 diabetes
Chairs: Irun Cohen (Rehovot), Naim Shehadeh (Haifa)
George Eisenbarth (Denver)
The Genetic Puzzle of Type 1 Diabetes with Insulin and the
MHC as Corner Pieces
Anette-Gabriele Ziegler (Munich)
Progression from autoimmunity to diabetes in man
Kevan Herold (New York)
Clinical efficacy and mechanisms of action of anti-CD3 mAb
in patients with new onset Type 1 diabetes
Jay Skyler (Miami)
Prevention of Type 1 diabetes - lessons learned , prospects
ahead
|
| 13:00 – 14:00 |
Lunch |
| 14:00 – 15:30
|
Session #2
Hypoglycemia / glucose sensors / complications
Chairs: Moshe Phillip (Tel Aviv), Julio Wainstein (Tel Aviv)
Stephanie Amiel (London)
Can hypoglycaemia be avoided in diabetes?
Bruce Buckingham (Stanford)
Hypoglycemia detection and Continuous Glucose Monitoring"
Mark Cooper (Melbourne)
Interaction of haemodynamic and metabolic
factors in diabetic nephropathy : focus on oxidative stress |
| 15:30 – 16:00 |
Coffee break |
| 16:00 – 18:00
|
Session #3
Stem cells
Chairs: Gil Leibowitz (Jerusalem), Pnina Vardi (Tel Aviv)
Joseph Itskovitz-Eldor
(Haifa)
Human embryonic stem cells: achievements and obstacles on the
path towards cell-based therapy
Nissim Benvenisty (Jerusalem)
Hepatic and pancreatic differentiation of human embryonic stem
cells
Yair Reisner (Rehovot)
Committed embryonic stem cells as a new source for transplantation
in diabetes
Camillo Ricordi
(Miami)
Challenges and opportunities in cellular therapies for diabetes |
| 08:00 – 09:00 |
Registration |
| 09:00
– 10:30 |
Session #4
Beta cell development
Chairs: Michael Walker (Rehovot),
Micha Rapoport (Tel Aviv)
Yuval Dor (Jerusalem)
Pancreatic beta cell regeneration
Helena Edlund (Umea)
Factors stimulating beta cell differentiation and function
Mark Magnuson (Nashville)
Multi-allelic gene targeting strategies and their application
to studies of beta cell development and function
|
| 10:30 – 11:00 |
Coffee break |
| 11:00 – 13:00 |
Session #5
New sources for surrogate beta cells
Chairs: Eddy Karnieli (Haifa), Avi Karasik (Tel Aviv)
Edward Baetge (San Diego)
Efficient production of definitive endoderm from hESCs
mimics developmental events occurring during gastrulation
Marvin Gershengorn (Bethesda)
Islet precursor cells from adult human islets
Shimon Efrat (Tel Aviv)
Expansion and re-differentiation of adult human islet cells
Sarah Ferber (Tel Aviv)
Using liver to replace beta cell function |
| 13:00 – 14:30 |
Lunch |
| 14:30 – 16:00
|
Session #6
Beta cell death and survival
Chairs: Ben Glaser (Jerusalem) and Yehiel Zick (Rehovot)
Decio Eizirik (Brussels)
Molecular regulation of beta cell death in type 1 diabetes mellitus
Danielle Melloul (Jerusalem)
Conditional and specific NF-kB blockade protects pancreatic
beta cells against diabetogenic agents
Marc Donath (Zurich)
Metabolic stress and islet inflammation
|
| 16:00 – 16:30 |
Coffee break |
| 16:30 – 17:30
|
Closing Keynote session
Chairs: Robert
Goldstein (New York), Itamar Raz (Jerusalem)
Philippe
Halban (Geneva)
New frontiers in the search for a cure: the beta cell to the
rescue !
|
