The Scientific Program - Neurodegenerative Diseases
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Saturday, April 06, 2019 |
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Hall D-CERVANTES |
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13:25-15:05 |
SESSION 38 | NEURODEGENERATIVE DISEASES |
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Chairpersons: |
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13:25-14:15 |
Are corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP) interchangeable terms? |
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Capsule: CBD and PSP are both 4 repeat tauopathies with rather heterogenous clinical presentations. However distinct differences underpin the notion that CBD and PSP are different diseases. Are these two manifestations of a spectrum disorder? This may have implications for designing future disease-modifying therapies. |
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13:25-13:35 |
Host: Isidro Ferrer, Spain |
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13:35-13:50 |
Yes: Lea Grinberg, USA/Brazil |
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13:50-14:05 |
No: Tamas Revesz, UK |
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14:05-14:15 |
Discussions and rebuttals |
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14:15-15:05 |
Are microbiota reasonable targets in the therapy of neurodegenerative diseases? |
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Capsule: The human microbiome consists of trillions of commensal microbes, including bacteria, fungi, and viruses, which naturally reside within the human body and have been documented to affect epigenetic mechanisims, metabolic activity, and immune function. Is there enough evidence to implicate the microbiome in neurodegenerative diseases? |
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14:15-14:25 |
Host: Ilana Schlesinger, Israel |
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14:25-14:40 |
Yes: Bogdan Popescu, Romania |
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14:40-14:55 |
No: Peter Jenner, UK |
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14:55-15:05 |
Discussion and rebuttals |
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15:05-15:20 |
Coffee Break |
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15:20-17:10 |
SESSION 39 | NEURODEGENERATIVE DISEASES |
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Chairpersons: |
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15:20-16:10 |
There is no need to define dementia sub-types in older patients, as the majority have mixed pathologies anyway. |
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Capsule: Researchers who examined older adults' brains after death found that most had two or more pathologies. Amyloid and tau were the most common pathology but rarely occurred alone. So, if the majority of older patients have mixed dementia, it may not be worthwhile to attempt to make a firm clinical diagnosis? |
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15:20-15:30 |
Host: Pierre Krolak-Salmon, France |
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15:30-15:45 |
Pro: Pasquale Calabrese, Switzerland |
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15:45-16:00 |
Con: Michael Ewers, Germany |
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16:00-16:10 |
Discussion and rebuttals |
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16:10-17:10 |
Round table discussion: Glia is centrally involved in the pathogenic process of degenerative diseases and should be a therapeutic target. Host: Antonio Federico, Italy and Rafael Franco, Spain |
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Speakers: Peter Jenner, UK , Roger Bullock, UK, Fernando de Castro, Spain, Lea Grinberg, USA/Brazil |
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END OF SATURDAY HALL D- CERVANTES |
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