Scientific Program - PDMD

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Please see below the CONy Scientific Program. Please click on the appropriate section (ordered by ABC) to view the relevant program. Please note that the program and timing is subject to change. To view the program timetable, please click here
 
Adamantiades-Behçet's disease The Brain and Mind Contursi Kindred
Dementia
Epilepsy
Headache / Sleep Multiple Sclerosis Neuroimmunology
Parkinson's disease &
Movement disorders
Rehabilitation / Neuromuscular Stroke

Section Heads: Maria Stamelou, Greece & Heinz Reichmann, Germany
SATURDAY, MARCH 25, 2017
Hall B
08:30-10:30
DEMENTIA WITH LEWY BODIES (DLB)
Chairs: Dimitrios Anastasopoulos, Greece; Giovanni Mirabella, Italy
Proposition: DLB and dementia of PD are the same disorder
Capsule:
Most PD patients develop ultimately dementia, while in some patients a-synuclein pathology involves cortical regions before the manifestation of parkinsonism. Do DLB and PDD represent different phenotypic manifestations of the same disease, or not?
Host: K. Jellinger, Austria
Pro: Irena Rektorova, Czech Republic
Con: Albert Ludolph, Germany
Discussion and rebuttals


Debate: DLB can be confidently diagnosed in patients who only have cognitive decline and REM-sleep behaviour disorder (RSBD).
Capsule: RSBD is present usually in alpha-synucleinopathies, however, it has also been described in Alzheimer’s disease and other dementias. In a patient with cognitive dysfunction and RSBD is DLB the most likely diagnosis?
Host:Sokratis Papageorgiou, Greece
Yes: Babak Tousi, USA
No: Paraskevi Sakka, Greece

Discussion and rebuttals

10:45-11:45 PD BIOMARKERS
Chairs: P. Stathis, Greece (TBC); Jaroslaw Slawek, Poland (TBC)
Debate: Is alpha-synuclein a useful biomarker in PD?
Capsule: Currently there is no biomarker for PD and this is urgently needed. There is controversial evidence as to whether alpha-synuclein, the pathological substrate of Lewy bodies, could serve as a valid biomarker in PD.
Host: Jesse Cedarbaum, USA
Yes: Albert Ludolph, Germany
No: Bogdan Popescu, Romania
Discussion and rebuttals


Debate: Is imaging very useful in the diagnosis of parkinsonism?
Capsule:
Brain Imaging may have some value in the diagnosis and management of parkinsonism, but there remains uncertainty regarding the generalizability of using MRI and dopamine imaging studies. Moreover, the sensitivity and specificity of imaging in differentiating between different parkinsonian disorders is controversial. Should imaging be routinely applied and is it really useful in the diagnosis of parkinsonism?
Host: Stuart Isaacson, USA
Yes: Marios Politis, UK
No: Maria Stamelou, Greece
Discussion and rebuttals

15:00-17:00
PATHOGENESIS
Chairs: Bostantjopoulou Sevasti, Greece;
Cristian Falup-Pecurariu, Romania
Proposition: The etiology of PD is predominantly genetic
Capsule: Increasing evidence supports the importance of genetic risk factors in the pathogenesis of PD. On the other hand, still, in the majority of the patients the disease is considered sporadic. Could genetics be the most predominant factor in the etiology of PD?
Host: Paolo Barone, Italy
Pro: Georgia Xiromerisiou, Greece
No: Heinz Reichmann, Germany

Discussion and rebuttals
Proposition: The gastrointestinal system is important in the pathogenesis of PD
Capsule: There is some evidence that PD could be initiated in the gut, and that the presence of alpha-synuclein aggregates or Lewy bodies in the enteric nervous system represents one of the earliest stages of the disease. On the other hand, there is evidence that does not fit to this hypothesis. Does PD start in the gut?

Host: Maria Stamelou, Greece
Pro: Bogdan Popescu, Romania
Con: Paolo Barone, Italy
Discussion and rebuttals

17:00-19:00
PDMD
Chairs: Rose Pons, Greece (TBC); Ilana Schlesinger, Israel
Debate: Is there enough evidence for the use of antipsychotics in PD psychosis?
Capsule:
PD psychosis is a common problem in clinical practice. A variety if antipsychotics and recent new ones have been widely applied in clinical practice. How evidence-based are these antipsychotic treatments for PD?
Host: Babak Tousi, USA
Pro: S. Isaacson, USA
No: Heinz Reichmann, Germany

Discussion and rebuttals

Debate: Is essential tremor a single entity?
Capsule: Essential tremor is thought to be the most common movement disorder. There is controversial evidence about its prevalence, phenomenology and pathology casting doubts on the common perception that ET is a single disorder. This debate will focus on evidence regarding this controversy

Host: K. Jellinger, Austria

Yes: Cenk Akbostanci, Turkey

No: Maria Stamelou, Greece

Discussion and rebuttals